Research - Scientific Studies Testing the Efficacy of Mushroom Nootropics

We believe that natural ingredients should be both powerful and purposeful. That’s why every capsule we make is formulated with research-backed functional mushrooms and botanicals—at dosages you can actually feel.

Functional mushrooms have been used for centuries to support cognitive health, immune balance, energy, and emotional resilience. Modern research continues to validate their benefits in areas like neurogenesis, stress regulation, and ATP production. Every blend is crafted around well-studied ingredients, chosen for synergy and effectiveness—not just label appeal.

Mushroom Research Library

Explore peer-reviewed studies organized by mushroom type or wellness benefit.


Clarity starts with transparency. That’s why every ingredient we use is listed here—nothing hidden, nothing extra. No synthetic stimulants, no fillers, and no additives. Just pure, functional mushrooms and botanicals chosen for their natural nootropic and adaptogenic benefits.
Lion’s Mane (Hericium erinaceus)
Supports memory, learning, and cognitive clarity by stimulating Nerve Growth Factor (NGF). Studied for its role in neurogenesis and nervous system repair. Lion's Mane is a staple in all of our blends!
Reishi (Ganoderma lucidum)
Often called the “mushroom of immortality,” Reishi helps regulate stress and support mood balance, while also strengthening immune response and reducing fatigue over time.
Chaga (Inonotus obliquus)
Rich in antioxidants, Chaga helps combat oxidative stress and supports long-term immune and cellular health, making it a powerful addition to daily wellness routines.
Turkey Tail (Trametes versicolor)
Packed with prebiotics and immune-supporting compounds, Turkey Tail promotes gut health and resilience, aiding in overall cognitive and physical vitality.
Cordyceps (Cordyceps militaris)
An adaptogenic fungus known to boost natural energy and endurance by enhancing oxygen utilization and ATP production at the cellular level.
Guarana (Paullinia cupana)
A natural source of caffeine that delivers smooth, sustained energy without the jitters, while supporting mental alertness and cognitive stamina.
Chaga Cancer – PubMed Study (PMID: 39204121) (year) Cancer – PubMed Study (PMID: 18203281) (year) Diabetes – PubMed Study (PMID: 28363167) (year) Infections & Immunity – PubMed Study (PMID: 23337743) (year) Inflammation – PubMed Study (PMID: 29321995) (year) Oxidative Stress – PubMed Study (PMID: 20416334) (year) Oxidative Stress – Research Article (year) Autoimmune – Research Article (year) Liver – Research Article (year)
Cordyceps Cancer – Research Article (year) Diabetes – Wiley Online Library Article (year) Infections & Immunity – PubMed Study (PMID: 23743169) (year) Fatigue – Research Article (year) Oxidative Stress – ScienceDirect Article (year) Oxidative Stress – PubMed Study (PMID: 24632182) (year) Autoimmune – PubMed Study (PMID: 24121015) (year) Liver – Research Article (year) Kidney – Research Article (year) Allergies & Asthma – ScienceDirect Article (year) Libido & Fertility – Research Article (year)
Guarana Cognitive Impairment – PubMed Study (PMID: 16533867) (year) Anxiety & Depression – Wiley Online Library Article (year) Diabetes – PubMed Study (PMID: 23612000) (year) Aging & Cognitive Decline – Research Article (year) Fatigue – Research Article (year) Oxidative Stress – ScienceDirect Article (year) Oxidative Stress – PubMed Study (PMID: 23981847) (year) Obesity & Weight – PubMed Study (PMID: 16418760) (year)
Lions Mane Cognitive Impairment – PubMed Study (PMID: 18844328) (year) Cognitive Impairment – PubMed Study (PMID: 27481299) (year) Anxiety & Depression – PubMed Study (PMID: 20834180) (year) Neuropathy - Nerves – PubMed Study (PMID: 21941586) (year) Stroke & TBI – Research Article (year) Gastrointestinal – PubMed Study (PMID: 18289813) (year) Cancer – PubMed Study (PMID: 25954910) (year) Diabetes – ScienceDirect Article (year) Aging & Cognitive Decline – Research Article (year) Autoimmune – PubMed Study (PMID: 26151021) (year)
Reishi Anxiety & Depression – ScienceDirect Article (year) Anxiety & Depression – PubMed Study (PMID: 15848033) (year) Cancer – PubMed Study (PMID: 23796215) (year) Cancer – PubMed Study (PMID: 16458355) (year) Diabetes – Research Article (year) Fatigue – Research Article (year) Oxidative Stress – PubMed Study (PMID: 24832113) (year) Autoimmune – ScienceDirect Article (year) Liver – ScienceDirect Article (year) Allergies & Asthma – PubMed Study (PMID: 18329205) (year)
Turkey Tail Gastrointestinal – PubMed Study (PMID: 28567446) (year) Cancer – PubMed Study (PMID: 22701135) (year) Cancer – PubMed Study (PMID: 12916709) (year) Diabetes – ScienceDirect Article (year) Infections & Immunity – PubMed Study (PMID: 18601990) (year) Infections & Immunity – Research Article (year) Fatigue – PubMed Study (PMID: 22701186) (year) Inflammation – PubMed Study (PMID: 29321995) (year) Oxidative Stress – PubMed Study (PMID: 29321995) (year) Autoimmune – PubMed Study (PMID: 25664323) (year)
Cognitive Impairment Lions Mane – PubMed Study (PMID: 18844328) (year) Guarana – PubMed Study (PMID: 16533867) (year) Lions Mane – PubMed Study (PMID: 27481299) (year)
Anxiety & Depression Lions Mane – PubMed Study (PMID: 20834180) (year) Reishi – ScienceDirect Article (year) Guarana – Wiley Online Library Article (year) Reishi – PubMed Study (PMID: 15848033) (year)
Neuropathy - Nerves Lions Mane – PubMed Study (PMID: 21941586) (year)
Stroke & TBI Lions Mane – Research Article (year)
Gastrointestinal Lions Mane – PubMed Study (PMID: 18289813) (year) Turkey Tail – PubMed Study (PMID: 28567446) (year)
Cancer Lions Mane – PubMed Study (PMID: 25954910) (year) Turkey Tail – PubMed Study (PMID: 22701135) (year) Chaga – PubMed Study (PMID: 39204121) (year) Reishi – PubMed Study (PMID: 23796215) (year) Cordyceps – Research Article (year) Turkey Tail – PubMed Study (PMID: 12916709) (year) Chaga – PubMed Study (PMID: 18203281) (year) Reishi – PubMed Study (PMID: 16458355) (year)
Diabetes Lions Mane – ScienceDirect Article (year) Turkey Tail – ScienceDirect Article (year) Chaga – PubMed Study (PMID: 28363167) (year) Reishi – Research Article (year) Cordyceps – Wiley Online Library Article (year) Guarana – PubMed Study (PMID: 23612000) (year)
Aging & Cognitive Decline Lions Mane – Research Article (year) Guarana – Research Article (year)
Infections & Immunity Turkey Tail – PubMed Study (PMID: 18601990) (year) Chaga – PubMed Study (PMID: 23337743) (year) Cordyceps – PubMed Study (PMID: 23743169) (year) Turkey Tail – Research Article (year)
Fatigue Turkey Tail – PubMed Study (PMID: 22701186) (year) Reishi – Research Article (year) Cordyceps – Research Article (year) Guarana – Research Article (year)
Inflammation Turkey Tail – PubMed Study (PMID: 29321995) (year) Chaga – PubMed Study (PMID: 29321995) (year)
Oxidative Stress Turkey Tail – PubMed Study (PMID: 29321995) (year) Chaga – PubMed Study (PMID: 20416334) (year) Reishi – PubMed Study (PMID: 24832113) (year) Cordyceps – ScienceDirect Article (year) Guarana – ScienceDirect Article (year) Chaga – Research Article (year) Cordyceps – PubMed Study (PMID: 24632182) (year) Guarana – PubMed Study (PMID: 23981847) (year)
Autoimmune Lions Mane – PubMed Study (PMID: 26151021) (year) Turkey Tail – PubMed Study (PMID: 25664323) (year) Chaga – Research Article (year) Reishi – ScienceDirect Article (year) Cordyceps – PubMed Study (PMID: 24121015) (year)
Liver Chaga – Research Article (year) Reishi – ScienceDirect Article (year) Cordyceps – Research Article (year)
Kidney Cordyceps – Research Article (year)
Allergies & Asthma Reishi – PubMed Study (PMID: 18329205) (year) Cordyceps – ScienceDirect Article (year)
Obesity & Weight Guarana – PubMed Study (PMID: 16418760) (year)
Libido & Fertility Cordyceps – Research Article (year)